Curriculum Vitae

Dr. Landon J. Getz, PhD

landon.getz@dal.ca

Executive Summary


Dr. Landon J. Getz (He/Him, PhD) is a Gay/Queer man and a molecular bacteriologist specializing in Vibrio genetics and phage-host Interactions in marine opportunistic pathogens. Dr. Getz is a CIHR Postdoctoral Fellow and the recipient of the inaugural GSK-EPIC Convergence Postdoctoral Fellowship at the University of Toronto. Landon is an LGBTQ+ advocate and has worked to enhance the equity, diversity, and inclusion of Science, Technology, Engineering, and Mathematics (STEM) through the founding of two community-building, advocacy organizations, Queer Atlantic Canadian STEM and more recently Pride in Microbiology. Landon is an alumnus of the inaugural Youth Council of the Chief Science Advisor of Canada.

Affiliations


Postdoctoral Fellow, Department of Biochemistry, Faculty of Medicine, University of Toronto

Education


Ph.D Microbiology and Immunology, Dalhousie University

B.Sc. First Class Honours in Microbiology and Immunology, Dalhousie University

Certificate in Genetics, Dalhousie University

Publications


Papers:

*Authors contributed equally to the work, #Corresponding Author.

  1. Getz, L.J., Maxwell, K.L.# (2024). Diverse anti-phage defences are widespread among prophages and mobile genetic elements. Annual Reviews of Virology DOI: 10.1146/annurev-virology-100422-125123.
  2. Patel, P.H., Taylor, V.L., Zhang, C., Getz, L.J, Fitzpatrick, A.D., Davidson, A.R., Maxwell, K.L.# (2024). Anti-phage defence through inhibition of virion assembly. Nature Communications. DOI: 10.1038/s41467-024-45892
  3. Getz, L.J., Brown, J.M., Sobot, L., Chow, A., Mahendrarajah, J., Thomas, N.A.# (2023). Attenuation of a DNA Cruciform by a Conserved Regulator Directs T3SS-1 mediated virulence in Vibrio parahaemolyticus. Nucleic Acids Research DOI: 10.1093/nar/gkad370.
  4. Kratzer, K.*, Getz, L.J.*, Peterlini, T, Masson#, J-Y, Dellaire, G#. (2021) “Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application.” Human Genetics. DOI: 10.1007/s00439-021-02272-5
  5. Getz, L.J., Dellaire, G.# (2020). “Back to Basics: Application of the 4-principle approach to bioethics to heritable genome editing.” Science and Engineering Ethics. DOI: 10.1007/s11948-020-00226-0.
  6. Getz, L. J., Runté, C., Rainey, J., Thomas, N.A.# (2019). “Tyrosine phosphorylation as a widespread regulatory mechanism in prokaryotes.” Journal of Bacteriology. DOI: 10.1128/JB.00205-19
  7. Thornbury, M.*, Sicheri, J.*, Slaine, P.D., Getz, L. J., Finlayson-Trick, E.C.L., Cook, J., Guinard, C., Boudreau, N., Jakeman, D., Rohde, J.R., McCormick, C.# (2018). “Characterization of novel lignocellulose-degrading enzymes from the porcupine microbiome using synthetic metagenomics” PLoS One. DOI: https://doi.org/10.1371/journal.pone.0209221.
  8. Getz, L.J.#, Dellaire, G.# (2018). “Angels and Devils: Dual-Use in Biotechnology.” Trends in Biotechnology. DOI: https://doi.org/10.1016/j.tibtech.2018.07.016.
  9. Runté, C., Jain, U., Getz, L.J., Secord, S., Kuwae, A., Abe, A., Leblanc, J., Stadnyk, A.W., Kaper, J.B., Hansen, A.M., Thomas, N.A.# (2018). “Tandem tyrosine phosphosites in the enteropathogenic Escherichia coli chaperone CesT are required for differential type III effector translocation and virulence.” Molecular Microbiology. DOI: https://doi.org/10.1111/mmi.13948.
  10. Getz, L.J., Thomas, N.A.##(2018) “The Transcriptional Regulator HlyU is a Positive Regulator for Expression of exsA Leading to Type III Secretion System-1 Activation in Vibrio parahaemolyticus Journal of Bacteriology. DOI: https://doi.org/10.1128/JB.00653-17.
  11. Getz, L.J.*, Finlayson-Trick, E.C.L.*, Slaine, P.D.*, Thornbury, M., Lamourerux, E., Cook, J., Langille, M.G.I., Murray, L.E., McCormick, C., Rohde, J.R., Cheng, Z.# (2017). “Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals.” PLoS One. DOI: https://doi.org/10.1371/journal.pone.0189404.

Commentaries and Correspondance:

  1. Getz, L.J#., de Oliveira, B.F.R. & Pérez-López, E. (2023) We need a Pride in Microbiology Network. Nat Microbiol. DOI: https://doi.org/10.1038/s41564-023-01394-y
  2. Qaiser, F., Laventure, A., Rilling, M., King, M., Johnson, C., Jakac-Sinclair, N., Getz, L.J., Cartile, A., Boulanger, M-E., Ammendolia, J. (2023). When youth voices are heard, science shines brighter. University Affairs
  3. Baylis, F., Getz, L.J. (2021). Challenge studies for COVID-19: Now is still not the timeJME Blog
  4. Getz, L.J.,, Baylis, F. (2021). Challenge studies for COVID-19: Now is not the time.JME Blog
  5. Getz, L.J., Baylis, F. (2020). Canada should reject the idea of deliberately infecting vaccine volunteers. PolicyOptions.ca
  6. Baylis, F., Getz, L.J. (2020). Why federal government should reject human challenge trials for COVID-19 vaccine. CBC Opinion.
  7. Qaiser, F., Morriseau, T., Rilling, M., Cartile, A., Sung, M., Getz, L.J., Boulanger, M-E. (2020). Envisioning A Post-Pandemic Future in the Canadian Science Community: A Youth Perspective. Canadian Science Policy Conference 2020
  8. Baylis, F., Getz, L.J. (2020). Rush to risky chellenge trials is unethical, HealthyDebate.ca.
  9. Getz, L.J. (2020). Rushing coronavirus vaccines and treatments could do more harm than good, TheConversation.ca, Republished in Everything Zoomer, and Dal News.
  10. Kofler, N., Getz, L.J., Baylis, F., Dellaire, G. (2019). Genetically modifying mosquitoes to control the spread of disease carries unknown risks, TheConversation.ca, republished in Salon, HalifaxToday.ca, SaltWire Newspapers, and Gannett Newspapers.
  11. Getz, L.J., Dellaire, G. (2019). Moratorium on Human Genome Editing: Time to Get It Right, The Hastings Center Forum Blog.
  12. Getz, L.J., Dellaire, G. (2019). CRISPR gene editing: Why we need Slow Science, The Conversation: Canada Edition.
  13. Getz, L.J. (2019).The “Value” of Consumer DNA Sequencing., Impact Ethics, Novel Tech Ethics, Halifax, NS.
  14. Getz, L.J., Dellaire, G., Baylis, F. (2018). “Jiankui He: A Sorry Tale of High-Stakes Science”, The Hastings Center Forum Blog.
  15. Baylis, F., Dellaire, G., Getz, L.J. (2018). “Why we are not ready for genetically designed babies”, The Conversation: Canada Edition. Reprinted in: The National Post and the Halifax Chronicle Herald.
  16. Getz, L.J. (2018). “Thicker Than Water: Slow Movement on Blood Policy”, Impact Ethics, Novel Tech Ethics, Halifax, NS.
  17. Getz, L.J. (2018). “The Privacy Implications of Human DNA Sequencing”, Impact Ethics, Novel Tech Ethics, Halifax, NS.
  18. Getz, L.J. (2017). “A Reflection on Blood Donation Policy in Canada”, Impact Ethics, Novel Tech Ethics, Halifax, NS.

Pre-Prints:

  1. Getz, L.J.*, Robinson, O.*, Thomas, N.A.# (2024). Functional Genomics of chtiin degradation by Vibrio parahaemolyticus reveals finely integrated metabolic contributions to support environmental fitness. BioRxiv.
  2. Getz, L.J., Brown, J.M., Sobot, L., Chow, A., Mahendrarajah, J., Thomas, N.A.# (2022). Attenuation of a DNA Cruciform by a Conserved Regulator Directs T3SS-1 mediated virulence in Vibrio parahaemolyticus. BioRxiv.
  3. *Thornbury, M., *Sicheri, J., Guinard, C,. Mahoney, D., Routledge, F,. Curry, M., Elaghil, M., Boudreau, N., Tsai, A., Slaine P., Finlayson-Trick, E.C.L., Getz, L.J., Cook, J., Rohde, J.R., McCormick, C. “Discovery and Characterization of Novel Lignocellulose-Degrading Enzymes from the Porcupine Microbiome.” BioRxiv.
  4. Runté, C., Jain, U., Getz, L.J., Secord, S., Kuwae, A., Abe, A., Leblanc, J., Stadnyk, A.W., Kaper, J.B., Hansen, A.M., Thomas, N.A. (2018) “Tandem tyrosine residues in the EPEC multicargo chaperone CesT support differential type III effector translocation and early host colonization.” BioRxiv.

Abstracts:

  1. Robinson, O., Getz, L.J., Thomas, N.A. {2023}. Transposon Sequencing Identifies a Genetic Paradigm for Chitin Utilization in Vibrio parahaemolyticus. 72nd Annual Conference of the Canadian Society of Microbiologists, Halifax, NS.
  2. Getz, L.J., Maxwell, K.L. (2023). Understanding the Global Antiphage Defence Arsenal of a Pandemic Foodborne Pathogen. 72nd Annual Conference of the Canadian Society of Microbiologists, Halifax NS.
  3. Getz, L.J., Maxwell, K.L.(2022). The Best Defence is a Good Offence: Understanding Antiphage Defence in V. parahaemolyticus for more Effective Phage Therapy. 2022 QAtCanSTEM Colloquium, Halifax, NS.
  4. Getz, L.J., Brown, J.M., Sobot, L., Chow, A., Mahendrarajah, J., Thomas, N.A. (2021). DNA Cruciforms Regulate Virulence in Pathogenic Vibrio Species. 70th Annual Conference of the Canadian Society of Microbiologists, Remote.
  5. Getz, L.J., Thomas. N.A. (2020). Functional genomics of \textit{Vibrio} pathogenesis and environmental persistence. 2020 Canadian Student Health Research Forum, Remote.
  6. Getz, L.J., Brown, J., Thomas, N.A. (2019). Type III Secretion System Gene Expression and Virulence is Regulated by a DNA Cruciform Structure at the exsA promoter in Vibrio parahaemolyticus, Genomes to Biology: the 8th International Conference on the Biology of Vibrios, McGill University, Montreal, QC.
  7. Getz, L.J., Brown, J., Thomas, N.A. (2019). A DNA junction superstructure regulates Type III Secretion System gene expression and virulence in Vibrio parahaemolyticus, The 69th Annual Conference of the Canadian Society of Microbiologists, Université de Sherbrooke, Sherbrooke, QC.
  8. Getz, L.J., Thomas, N.A. (2018). Flipping the Switch on Bacterial Pathogenesis: How the Leading Cause of Seafood-borne Gastroenteritis - Vibrio parahaemolyticus - Regulates Virulence, LGBTSTEMinar 2019, Institute of Physics, London, UK.
  9. Getz, L.J., Comeau, A., Langille, M.G.I., Thomas, N.A. (2018). Linking Phenotype and Pathogen Genomics: Tn-Seq and Next Generation DNA Sequencing, PREP Graduate Student Research Day, Dalhousie University, Halifax, NS.
  10. Getz, L.J., Comeau, A., Langille, M.G.I., Thomas, N.A. (2018). Linking Phenotype and Pathogen Genomics: Tn-Seq and Next Generation DNA Sequencing, 23rd Annual Infectious Disesase Research Day, Dalhousie University, Halifax, NS.
  11. Getz, L.J., Thomas, N.A. (2017). HlyU and H-NS Act as a Genetic Switch for Transcriptional Control of the Type III Secretion System-I Master Regulator exsA, ASM Vibrio2017: The Biology of Vibrios, Chicago, IL.
  12. Getz, L.J., Thomas, N.A. (2017). Discovery of a Genetic Switch in Vibrio parahaemolyticus That Contributes to Host Cell Death During Infection, 22nd Annual Infectious Disease Research Day, Dalhousie University, Halifax, NS.
  13. Getz, L.J., Finlayson-Trick, E.C.L.*, Mostafa Hagar*, Slaine, P.D., Thornbury, M., Lamourerux, E., Cook, J., Langille, M.G.I., Murray, L.E., McCormick, C., Rohde, J.R., Cheng, Z.A ‘spike’ in biofuel production: mining the porcupine microbiome to engineer a softwood feedstock platform, Giant Jamboree Abstract Guide, iGEM Giant Jamboree, Boston, MA.

Invited Talks


2nd Annual Antimicrobial Resistance Symposium, Emerging and Pandemic Infections Consortium, Toronto, ON - November 2023

2023 Connell Award for Best All Round Post Doctoral Fellow Award Lecture, 2023 Annual Biochemsitry Retreat, Toronto, ON - October 2023

2022 Armand-Frappier Outstanding Graduate Student Award Lecture, 71st Annual Conference of the Canadian Society of Microbiologists, Guelph, ON - June 2022

2022 Al Downe Memorial Lecture, Queen’s University, Kingston, ON - March 2022

Genomics in Medicine - Emerging Technologies and Bioinformatic Challenges, Dalhousie University, Halifax, NS. - December 2019

Graduate Student Research Day Excellence in Research Keynote, Dalhousie University, Halifax, NS. - May 2019

Natural History Museum Life Science Seminar Series - London, UK - January 2019

Conference and Seminar Presentations


For Posters: *Presenting Author

  1. Vibrio2024: The International Meeting on the Biology of Vibrios, Lima, Peru - October 2024
    • Type: Oral Presentation
    • Title: Vibrio parahaemolyticus integrons encode novel antiphage defence
  2. 73rd Annual Conference of the Canadian Society of Microbiologists, Western University, London, ON - June 2024
    • Authors: Getz, L.J.*, Fairburn, S., Liu, V., Qian, A.Y., Maxwell, K.L.
    • Type: Poster Presentation
    • Title: Identification of a Novel Phage Defence Hotspot in Vibrio parahaemolyticus
  3. 73rd Annual Conference of the Canadian Society of Microbiologists, Western University, London, ON - June 2024
    • Authors: Qian, L.A.*, Getz, L.J., Maxwell, K.L.
    • Type: Poster Presentation Title: Novel DNA glycosylase-based enzyme restricts phage replication in Vibrio parahaemolyticus
  4. 72nd Annual Conference of the Canadian Society of Microbiologists, Halifax, NS - June 2023.
    • Authors: Robinson, O.*, Getz, L.J., Thomas, N.A.
    • Type: Poster Presentation
    • Title: Transposon Sequencing Identifies a Genetic Paradigm for Chitin Utilization in Vibrio parahaemolyticus.
  5. 72nd Annual Conference of the Canadian Society of Microbiologists, Halifax, NS - June 2023.
    • Authors: Getz, L.J.*, Maxwell, K.L.
    • Type: Poster Presentation
    • Title:Understanding the Global Antiphage Defence Arsenal of a Pandemic Foodborne Pathogen.
  6. 2022 QAtCanSTEM Colloquium, Halifax, NS - October 2022.
    • Authors: Getz, L.J.*, Maxwell, K.L.
    • Type: Poster Presentation
    • Title: The Best Defence is a Good Offence: Understanding Antiphage Defence in V. parahaemolyticus for more Effective Phage Therapy.
  7. 70th Annual Conference of the Canadian Society of Microbiologists, University of Guelph, Guelph, ON - June 2021
    • Type: Oral Presentation
    • Title: DNA Cruciforms Regulate Virulence Gene Expression in Pathogenic Vibrio Species.
    • Awarded the 2021 Canadian College of Microbiologists Symposium Award.
  8. Canadian Science Policy Conference, University of Ottawa, Ottawa, QC - October 2020.
    • Type: Oral Presentation and Roundtable
    • Title: Build Back Better: The Chief Science Advisor’s Youth Council’s Roundtables to Envision a Post-Pandemix Future in the Canadian Science Community.
  9. Canadian Student Health Research Forum, University of Manitoba, Regina, MB - August 2020.
    • Type: Oral Presentation
    • Title: Functional genomics of Vibrio pathogenesis and environmental persistence.
    • Awarded a CIHR Silver Award
  10. 70th Annual Conference of the Canadian Society of Microbiologists, Remote- June 2020
    • Type: Oral Presentation
    • Title: A DNA Cruciform Structure Regulates Virulence Gene Expression in Human Pathogenic Vibrio species.
  11. Professional Research and Education Program Graduate Student Research Day, Dalhousie University, Halifax, NS - May 2020
    • Type: Oral Presentation
    • Title: A Regulator of Sugar Metabolism Implicated in the Secretion and Virulence of Vibrio parahaemolyticus.
  12. Genomes to Biology: The 8th International Conference on the Biology of Vibrios, McGill University, Montreal, QC - November 2019
    • Type: Oral Presentation
    • Title: Type III Secretion System Gene Expression and Virulence is Regulated by a DNA Cruciform Structure at the exsA promoter in Vibrio parahaemolyticus
    • Awarded a People’s Choice Award by the Canadian Society of Microbiologists.
  13. Centre for Comparative Genomics and Evolutionary Bioinformatics Research Retreat, Dalhousie University, Halifax, NS - November 2019
    • Authors: Landon J. Getz*, Justin Brown, Nikhil Thomas
    • Type: Poster Presentation
    • Title:Type III Secretion System Gene Expression and Virulence is Regulated by a DNA Cruciform Structure at the exsA promoter in Vibrio parahaemolyticus
  14. 69th Annual Conference of the Canadian Society of Microbiologists, Université de Sherbrooke, Montreal, QC - June 2019
    • Authors: Landon J. Getz, Justin Brown, Nikhil Thomas*
    • Type: Poster Presentation
    • Title: A DNA junction superstructure regulates Type III Secretion System gene expression and virulence in Vibrio parahaemolyticus
  15. Professional Research and Education Program Graduate Student Research Day, Dalhousie University, Halifax, NS. - May 2019
    • Type: Oral Presentation
    • Title: A Regulator of Sugar Metabolism Implicated in the Secretion and Virulence of Vibrio parahaemolyticus
  16. Dalhousie Conference on University Teaching and Learning, Dalhousie University, Halifax, NS. - May 2019
    • Type: Oral Presentation
    • Title: Creating LGBTQ+ Inclusive Spaces for Equitable Active Learning
  17. Microbiology and Immunology Seminar Series, Dalhousie University, Halifax, NS. - January 2019
    • Type: Oral Presentation
    • Title: The Multimodal Lifestyle of Marine Vibrios
  18. LGBTSTEMinar 2019, Institue of Physics, London, UK - January 2019
    • Type: Oral Presentation
    • Title: Flipping the Switch on Bacterial Pathogenesis: How the Leading Cause of Seafood-borne Gastroenteritis - Vibrio parahaemolyticus - Regulates Virulence
  19. PREP Graduate Student Research Day, Dalhousie University, Halifax, NS - May 2018
    • Type: Oral Presentation
    • Title: Linking Phenotype and Pathogen Genomics: TnSeq and Next Generation DNA Sequencing
  20. 23rd Annual Infectious Disease Research Day, Centre for Vaccinology, Halifax, NS - April 2018
    • Authors: Landon J. Getz*, André Comeau, Morgan G. I. Langille, Nikhil Thomas
    • Type: Poster Presentation
    • Title: Linking Phenotype and Pathogen Genomics: TnSeq and Next Generation DNA Sequencing.
  21. Microbiology and Immunology Graduate Student Seminar, Dalhousie University, Halifax, NS - February 2018
    • Type: Oral Presentation
    • Title: Vibrio parahaemolyticus: A Versatile Pathogen Living a Dual-Lifestyle
  22. ASM Vibrio2017, American Society of Microbiology, Chicago, IL - November 2017
    • Authors: Landon J. Getz*, Nikhil Thomas
    • Type: Poster Presentation
    • Title: HlyU and H-NS act as a Genetic Switch for Transcriptional Control of the Type-III Secretion System I Master Regulator exsA
  23. 22rd Annual Infectious Disease Research Day, Dalhousie University, Halifax, NS - April, 2017
    • Authors: Landon J. Getz*, Nikhil Thomas
    • Type: Poster Presentation
    • Title: Discovery of a Genetic Switch in Vibrio parahaemolyticus that Contributes to Host Cell Death during Infection.
  24. 2016 iGEM Giant Jamboree, iGEM, Boston, MA - October 2016
    • Authors: Getz, L.J.*, Finlayson-Trick, E.C.L.*, Mostafa Hagar*, Slaine, P.D., Thornbury, M., Lamourerux, E., Cook, J., Langille, M.G.I., Murray, L.E., McCormick, C., Rohde, J.R., Cheng, Z.
    • Type: Poster Presentation
    • Title: Biofuel Production set to Spike: Identification of Biofuel Producing Enzymes in the Porcupine Microbiome
  25. 2016 iGEM Giant Jamboree, iGEM, Boston, MA - October, 2016
    • Type: Oral Presentation
    • Title: Biofuel Production set to Spike: Identification of Biofuel Producing Enzymes in the Porcupine Microbiome
  26. Microbiology and Immunology Seminar Series, Dalhousie University, Halifax, NS - September 2016
    • Type: Oral Presentation
    • Title: State of the Union: iGEM Introduction

Teaching and Mentoring


A Complete Teaching Dossier can be found here.

Knowledge Translation


Awards:


Service


Scientific Peer Review:

Grant Review

Pre-print review:

Conference Planning

Governmental:

Society:

Institutional:

Other:

Media


Previous Work Experience